Ngwaahịa
Pepsin nke Deebio maka ọgwụgwọ dyspepsia kpatara site n'ịṅụbiga nri protein
Nkọwa
1. Characters: White ma ọ bụ ubé odo, crystalline ma ọ bụ amorphous ntụ ntụ.
2. Isi mmalite: Porcine gastric mucosa.
3. Usoro: Pepsin dịpụrụ adịpụ site na mucosa gastric pig na-eji usoro mmịpụta pụrụ iche.
4. Ngosipụta na ojiji: A na-ejikarị ya eme ihe maka dyspepsia kpatara site na ịṅụbiga nri protein, digestive hypofunction na oge mgbake na enweghi proteinase nke afo kpatara nke na-adịghị ala ala atrophic gastritis, cancer gastric cancer and malignant anaemia.Pepsin bụ enzyme nke zoro ezo. n'usoro digestive nke mammals.Ọ na-arụ ọrụ ịkụda protein n'ime peptides pere mpe nke obere eriri afọ nwere ike ịmịnye ya ngwa ngwa.
5. Biochem/physiol Actions: N'adịghị ka ọtụtụ peptidases ndị ọzọ, pepsin hydrolyzes naanị peptide bonds, ọ bụghị amide ma ọ bụ ester linkages.Nkọwapụta nkewa ahụ na-agụnye peptides nwere acid aromatic n'akụkụ abụọ nke njikọ peptide, karịsịa ma ọ bụrụ na ihe fọdụrụnụ bụkwa aromatic ma ọ bụ amino acid dicarboxylic.Mmụba ike nke hydrolysis na-eme ma ọ bụrụ na enwere amino acid nwere sọlfọ dị nso na njikọ peptide, nke nwere amino acid aromatic.Pepsin ga-amachakwa mma ịrapawa n'akụkụ carboxyl nke phenylalanine na leucine, yana n'ókè dị nta na akụkụ carboxyl nke glutamic acid residues.Ọ naghị ekewa na valine, alanine, ma ọ bụ glycine njikọ.ZL-tyrosyl-L-phenylalanine, ZL-glutamyl-L-tyrosine, ma ọ bụ ZL-methionyl-L-tyrosine nwere ike iji dị ka ihe maka mgbaze pepsin.A na-egbochi Pepsin site na ọtụtụ peptides nwere phenylalanine.
Gịnị mere anyị?
· Gafere GMP China na EU GMP
· afọ 27 nke akụkọ ihe mere eme nke enzyme R&D
· A na-achọpụta ihe ọkụkụ
Soro CP, EP, USP na ọkọlọtọ ndị ahịa
· Ọrụ dị elu, ịdị ọcha dị elu, nkwụsi ike dị elu
· Mbupụ gaa na mba na mpaghara iri atọ
· Nwere ikike nke njikwa sistemụ dị mma dịka US FDA, Japan PMDA, South Korea MFDS, wdg.
Nkọwapụta
| Nnwale ihe | Nkọwapụta ụlọ ọrụ | |||
| CP | EP | USP | ||
| Ndị agwa | White ka ìhè odo ntụ ntụ; | Ọcha ma ọ bụ ntakịrị odo, | Ọcha ma ọ bụ ntakịrị odo, | |
| enweghị mildew na deodorant;hygroscopic, | crystalline ma ọ bụ amorphous ntụ ntụ | crystalline ma ọ bụ amorphous ntụ ntụ | ||
| ngwọta mmiri na-egosi mmeghachi omume acidic | ||||
| njirimara | Dabara | Dabara | Dabara | |
| Nnwale | Ọnwụ na ihicha | ≤ 5.0% (Akọrọ gburugburu100℃, 4h) | ≤ 5.0% (670Pa 60℃, 4h) | ≤ 5.0% (Vacuum decompression 60℃, 4h) |
| Ihe mgbaze fọdụrụnụ | ———— | ≤ 5.0% Dị ka EP (5.4) si kwuo | ≤ 5.0% Dị ka USP (467) si kwuo | |
| Nyocha | 3800 ~ 12000U/g | 0.5～4.5 Ph.Eur.U./mg | 3000 ~ 20000NF.U/mg | |
| Microbial | TAMC | ≤5X103cfu/g | ≤10000cfu/g | ≤10000cfu/g |
| Ihe adịghị ọcha | TYMC | ≤100cfu/g | ≤100cfu/g | ≤100cfu/g |
| E.coli | Dabara | Dabara | Dabara | |
| Salmonella | Dabara | Dabara | Dabara | |
